Perceived stigmatization is common among patients with NAFLD, study finds & More Trending News

About seven out of ten patients (69%) that suffer from non-alcoholic fatty liver illness (NAFLD) understand some stigmatization of their day by day life, based on a study led by a workforce of the University of Barcelona, the Liver and Digestive Diseases Networking Biomedical Research Centre (CIBEREHD), the Hospital Clínic de Barcelona and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS). According to the study, printed within the journal PLoS ONE, the stigma these patients understand is additionally related with the impaired high quality of life which is common in individuals affected by NAFLD.

Stigma in liver illnesses

Liver illnesses are thought of to be stigmatized —a well-documented downside in sure pathologies—, most likely as a result of they’re related with alcoholism and drug abuse. Some research confirmed that patients affected by hepatitis C and B are sometimes stigmatized whatever the methodology of transmission of the virus, whereas patients with liver cirrhosis are additionally stigmatized whatever the etiology of the illness. However, there is little data on the stigma in patients with non-alcoholic fatty liver illness. Therefore, the study aimed to discovering the frequency and options of the perceived stigma among patients with NAFLD.

The non-alcoholic fatty liver illness is probably the most common liver pathology worldwide —it impacts almost the 24% of the world inhabitants— and it is typically related with weight problems and the metabolic syndrome. A big a part of the patients affected by this progressive illness evolve from a easy steatosis to cirrhosis or hepatocellular carcinoma.

It is attainable for NAFLD to be a stigmatized illness as a result of it impacts the liver and it is often linked to weight problems, two situations that are common drivers of stigma. “

Marta Carol, researcher, UB-CIBEREHD-CLINIC-IDIBAPS and one of many principal authors of the study

As a part of the study, the workforce collected knowledge from 197 patients from the Hepatology Department of Hospital Clínic de Barcelona, 114 of them being affected by NAFLD and 53 with alcohol-related cirrhosis. Since NAFLD is often related with an impaired high quality of life, additionally they explored the potential relationship between the perceived stigma and the standard of life of those patients. The perceived stigma was evaluated by a particular questionnaire listed in 4 domains: stereotypes, discrimination, disgrace, and social isolation.

Stereotypes, discrimination, disgrace and social isolation

The 69% of the NAFLD patients really feel stigmatized, a situation that impacts the 4 analysed domains, based on the conclusions. Among the patients with NAFLD, the sensation of stigma was larger in patients whose illness had advanced to cirrhosis (72%) in comparison with patients with out cirrhosis (67%).

Among the patients with cirrhosis, stigmatization was extra common in alcohol-related cirrhosis than in NAFLD, though the variations had been important in two domains. Moreover, in patients with NAFLD, the perceived stigma corresponded to a nasty high quality of life.

“Stigmatization is a relevant issue in many diseases due to its potential negative impact on the mental status of the patients, plus it reduces the possibility for these people to access recovery and care”, notes Pere Ginès, professor on the Faculty of Medicine and Health Sciences, member of CIBEREHD, Hospital Clinic and IDIBAPS, and one of many coordinators of the analysis. “In these recent years, there has been a growing interest in the fight against stigmatization of certain diseases to improve the social acceptance of patients and overall health status”, notes Ginès.

“The perceived stigmatization —says the research team— is common among patients with NAFLD regardless of the stage of their disease, it is associated with an impaired quality of life and can be the cause for stereotypes, discrimination, shame and social isolation, which can affect the patients’ human and social rights”.

Therefore, “the results of this study represent a warning sign on the importance of this perceived stigma in patients with NAFLD, which has consequences in sensitive areas of life. We believe that healthcare professionals, patients associations, and policymakers must consider these findings to promote research and encourage initiatives aimed at preventing discrimination of people affected by this disease”, conclude the authors.

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