Washington, D.C. – June 11, 2022 – T cell testing utilizing a industrial T cell test, QuantiFERON SARS-CoV-2 RUO, gives perception into the immune response to an infection and vaccination of sufferers with COVID-19 and means that age and time from an infection are vital factors associated to the magnitude of cell-mediated immune (CMI) responses to COVID-19. The findings are introduced at ASM Microbe 2022, the annual assembly of the American Society for Microbiology.
Conclusions of the brand new findings are primarily based on proof from an observational scientific research involving human topics carried out from June 2021 to February 2022 within the United States and Netherlands. SARS-CoV-2 T cell assessments can present researchers and clinicians with details about a person’s capability to struggle future COVID-19 an infection. QuantiFERON SARS-CoV-2 RUO, a industrial T cell test, detected T cell mediated immune responses in 80% of scientific research topics who accomplished COVID-19 vaccination within the earlier 24 weeks (6 months).
When evaluating what factors could affiliate with poor T cell responses noticed after vaccination, solely rising age considerably related with poor T cell response. Time from vaccination, sort of vaccine acquired, or gender weren’t related with T cell response. In topics who had been contaminated with SARS-CoV-2, QuantiFERON SARS-CoV-2 RUO detected T cell responses in 74% of topics who had been contaminated within the earlier 24 weeks. The solely issue related with poor T cell responses after an infection was time elapsed after an infection.
“This study reinforces current knowledge connecting increasing age and time from infection with diminished immunity to SARS-CoV-2, which may, in turn, contribute to greater susceptibility to infection and subsequent disease,” stated Robin Uchiyama, Clinical Study Lead, Clinical Affairs at QIAGEN and the lead creator on the research. “This work highlights the importance of T cell testing and implementing robust preventative measures against infection, like vaccination, boosters and masking, even after vaccination in older adults or after infection.”
The QIAGEN-funded work was led by QIAGEN’s Clinical Affairs group primarily based in Germantown, Md. and will probably be introduced at ASM Microbe in Washington, D.C. on Saturday, June 11, 2022.
Commercial T cell test finds factors correlated with diminished T cell responses to Covid & More Latest News Update
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