Heche, best known for 1990s movies Donnie Brasco and Six Days, Seven Nights as well as a high-profile relationship with talk show host Ellen DeGeneres, crashed her car into a two-storey house in the Mar Vista neighbourhood of Los Angeles.
The violent collision resulted in “structural compromise and… heavy fire” at the scene, according to the Los Angeles Fire Department.
The ensuing blaze took 59 firefighters more than an hour to contain and fully extinguish, the department said.
Local media reported Thursday that preliminary tests of Heche’s blood had come back positive for narcotics, though more were needed to ensure the drugs had not been administered in the course of her treatment.
Celebrity gossip outlet TMZ, citing unnamed police sources, said Heche had tested positive for cocaine and fentanyl, with the latter sometimes used for pain relief in clinical settings.
Heche rose to fame with her role on the soap opera Another World, for which she won a Daytime Emmy in 1991.
She was nominated for a Tony award for her appearance in Twentieth Century on Broadway in 2004.
“My brother Atlas and I lost our Mum,” Heche’s son Homer Laffoon said in a separate statement.
“Hopefully my mum is free from pain and beginning to explore what I like to imagine as her eternal freedom,” he wrote.
Actress Anne Heche dies after car crash & Latest News Update
Actress Anne Heche dies after car crash & More Live News
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