Surgeon on trial in Sweden over experimental windpipe transplants

An Italian physician who made headlines for pioneering windpipe surgical procedure has gone on trial in Sweden, charged with aggravated assault for performing the experimental process.

Paolo Macchiarini gained reward in 2011 after claiming to have carried out the world’s first artificial trachea transplants utilizing stem cells whereas he was a surgeon at Stockholm’s Karolinska Institute.

The process was hailed as a breakthrough in regenerative medication.

But allegations quickly emerged that the dangerous process had been carried out on a minimum of one one that had not been critically ailing on the time of the operation.

The 63-year-old appeared in courtroom on Wednesday, the place he listened to translated audio as prosecutors listed the costs of “aggravated assault” towards three sufferers.

The Karolinska Institute has confirmed that the three people have since died, however didn’t immediately hyperlink the deaths to the operations.

“Macchiarini has carried out the surgery with complete disregard for science and tried experience,” prosecutor Karin Lundström-Kron instructed the courtroom.

As prosecutors offered their case they referenced each exterior and inner evaluations of the case, together with one revealed in 2016 by doctor Kjell Asplund, who argued that Macchiarini ought to by no means have been employed by Karolinska in the primary place.

“It is clear that this method has not worked,” prosecutor Jim Westerberg mentioned, including that Macchiarini had embellished the advantages of the process.

Macchiarini, who took notes with out exhibiting a lot emotion, has maintained the operations constituted remedies and never experiments, and denied being criminally accountable.

“He contends that he has performed healthcare, cured and helped,” Macchiarini’s lawyer, Björn Hurtig, instructed AFP throughout a recess.

The prosecution’s presentation of proof is anticipated to proceed over a number of days so the defence is unlikely to current its aspect till subsequent week.

But Hurtig mentioned that they had “high hopes” they might be capable to counter the prosecution’s proof. “There are quite a lot of gaps in that evidence and there is a lot of evidence that we argue are favourable to our view of things,” he mentioned.

In 2013, the Karolinska hospital suspended all transplants and refused to increase Macchiarini’s contract as a surgeon. A 12 months later, a number of surgeons on the hospital filed a criticism alleging that Macchiarini had downplayed the dangers of the process.

Macchiarini carried out three surgical procedures at Karolinska University hospital in 2011 and 2012, utilizing a man-made windpipe manufactured from plastic and coating it with the affected person’s personal stem cells.

Together along with his colleagues, he carried out eight such transplants between 2011 and 2014, the 5 others happening in Russia.

An exterior evaluate in 2015 discovered Macchiarini responsible of analysis misconduct, however regardless of sacking him, the Karolinska Institute repeatedly defended him till 2018, when it discovered him and a number of other different researchers responsible.

The college’s principal stepped down over the scandal, in addition to various others.

In 2018, the Lancet medical journal retracted two papers authored by Macchiarini.

The trial, held in the Solna district courtroom close to the Karolinska Institute, is scheduled to happen over 13 days.

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